Abstract
To determine whether a multihospital Clostridium difficile outbreak was associated with epidemic strains and whether use of particular fluoroquinolones was associated with increased infection rates, we cultured feces from C. difficile-infected patients. Use of fluoroquionolones with enhanced antianaerobic activity was not associated with increased infection rates.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Anti-Infective Agents / therapeutic use
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Aza Compounds / therapeutic use
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Clostridioides difficile / drug effects
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Clostridioides difficile / genetics
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Clostridioides difficile / isolation & purification*
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Clostridium Infections / drug therapy
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Clostridium Infections / epidemiology*
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Clostridium Infections / microbiology
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Cross Infection / drug therapy
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Cross Infection / epidemiology*
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Cross Infection / microbiology
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Disease Outbreaks*
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Drug Resistance, Bacterial
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Feces / microbiology
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Fluoroquinolones / therapeutic use
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Gatifloxacin
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Genes, Bacterial
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Hospitals*
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Humans
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Moxifloxacin
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Ohio / epidemiology
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Quinolines / therapeutic use
Substances
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Anti-Infective Agents
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Aza Compounds
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Fluoroquinolones
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Quinolines
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Gatifloxacin
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Moxifloxacin