Abstract
In Singapore, after a major outbreak of dengue in 2005, another outbreak occurred in 2007. Laboratory-based surveillance detected a switch from dengue virus serotype 1 (DENV-1) to DENV-2. Phylogenetic analysis showed a clade replacement within DENV-2 cosmopolitan genotype, which accompanied the predominant serotype switch, and cocirculation of multiple genotypes of DENV-3.
MeSH terms
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Aedes / virology
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Animals
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Dengue / epidemiology*
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Dengue / virology
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Dengue Virus / classification
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Dengue Virus / genetics*
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Dengue Virus / isolation & purification
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Disease Outbreaks
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Humans
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Insect Vectors / virology
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Molecular Sequence Data
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Mosquito Control
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Phylogeny
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Population Surveillance*
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RNA, Viral / analysis
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RNA, Viral / genetics
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Sequence Analysis, DNA
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Serotyping
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Singapore / epidemiology
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Viral Envelope Proteins / analysis
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Viral Envelope Proteins / genetics
Substances
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RNA, Viral
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Viral Envelope Proteins