Abstract
cis-Dihydrocatechols, derived from biological cis-dihydroxylation of methyl benzoate, iodobenzene and benzonitrile, using the microorganism Pseudomonas putida UV4, were converted into pericosines A, C, and B, respectively. This approach constitutes the shortest syntheses, to date, of these important natural products with densely packed functionalities.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Molecular Conformation
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Naphthalenes / chemistry*
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Shikimic Acid / analogs & derivatives*
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Shikimic Acid / chemical synthesis
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Shikimic Acid / chemistry
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Stereoisomerism
Substances
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Naphthalenes
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methyl (3S,4S,5S,6S)-6-chloro-3,4,5-trihydroxy-1-cyclohexene-1-carboxylate
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pericosine B
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pericosine C
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trans-1,2-dihydro-1,2-naphthalenediol
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Shikimic Acid