This case demonstrates that laparoscopic-assisted enteroscopy (LAE) is a safe and effective technique to aid diagnosis and treatment of small bowel lesions that are difficult to identify with traditional and advanced imaging and interventional techniques. In patients where definite bowel lesions are identified on small bowel capsule endoscopy or small bowel enteroscopy, LAE can be extremely valuable in pinpointing the lesion intra-operatively. This technique may have certain merit for laparoscopic Crohn's stricturoplasty.