Abstract
The triple-helical structure of collagen peptides has recently been harnessed as a subunit in the higher-order assembly of unique biomaterials. Specific assembly signals have been designed within collagen peptides, including hydrophobic groups, electrostatic interactions, and metal-ligand binding, to name a few. In this way, a range of novel assemblies have been obtained, including nano- to microscale fibers, gels, spheres, and meshes, each with the potential for novel biological applications in drug delivery, tissue engineering, and regenerative medicine.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, U.S. Gov't, Non-P.H.S.
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Review
MeSH terms
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Biocompatible Materials / analysis
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Biocompatible Materials / chemistry*
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Biocompatible Materials / metabolism
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Collagen / analysis
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Collagen / chemistry*
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Drug Delivery Systems / adverse effects
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Extracellular Matrix / chemistry*
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Extracellular Matrix / metabolism
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Manufactured Materials / analysis
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Peptides / analysis
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Peptides / chemistry*
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Peptides / metabolism*
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Tissue Engineering / methods
Substances
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Biocompatible Materials
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Peptides
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Collagen