Evaluation of the analytical performance of the Nova StatSensor creatinine meter and reagent strip technology for whole blood testing

Kareena L Schnabl; Sousan Bagherpoor; Pauline Diker; Christine Cursio; Jeffrey Dubois; Paul M Yip

doi:10.1016/j.clinbiochem.2010.04.055

Evaluation of the analytical performance of the Nova StatSensor creatinine meter and reagent strip technology for whole blood testing

Clin Biochem. 2010 Aug;43(12):1026-9. doi: 10.1016/j.clinbiochem.2010.04.055. Epub 2010 Apr 21.

Authors

Kareena L Schnabl¹, Sousan Bagherpoor, Pauline Diker, Christine Cursio, Jeffrey Dubois, Paul M Yip

Affiliation

¹ Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Ontario M5S1A8, Canada.

PMID: 20416292
DOI: 10.1016/j.clinbiochem.2010.04.055

Abstract

Objective: To evaluate the analytical performance of the Nova StatSensor creatinine meter.

Design and methods: Imprecision, linearity, patient correlation and interference studies were completed.

Results: Total imprecision was 4.5-9.1%CV and a linear measurement range of 93-863 micromol/L (1.05-9.76 mg/dL) was verified. Whole blood creatinine results correlated well with laboratory plasma measurements (R(2)=0.9328) but exhibited a negative proportional bias. In vitro, high levels of creatine and urea falsely elevated creatinine measurement.

Conclusions: The creatinine meter provides reliable measurement across a clinically relevant range and has potential use in point-of-care testing.

Publication types

Evaluation Study

MeSH terms

Creatinine / blood*
Humans
Point-of-Care Systems
Reagent Strips*
Reproducibility of Results

Substances

Reagent Strips
Creatinine