MR to ultrasound image registration for guiding prostate biopsy and interventions

Med Image Comput Comput Assist Interv. 2009;12(Pt 1):787-94. doi: 10.1007/978-3-642-04268-3_97.

Abstract

A method is described for registering preoperative magnetic resonance (MR) to intraoperative transrectal ultrasound (TRUS) images of the prostate gland. A statistical motion model (SMM) of the prostate is first built using training data provided by biomechanical simulations of the motion of a patient-specific finite element model, derived from a preoperative MR image. The SMM is then registered to a 3D TRUS image by maximising the likelihood of the shape of an SMM instance given a voxel-intensity-based feature, which represents an estimate of normal vector at the surface of the prostate gland. Using data acquired from 7 patients, the accuracy of registering T2 MR to 3D TRUS images was evaluated using anatomical landmarks inside the gland. The results show that the proposed registration method has a root-mean-square target registration error of 2.66 mm.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Artificial Intelligence
  • Biopsy / methods*
  • Humans
  • Image Enhancement / methods
  • Image Interpretation, Computer-Assisted / methods*
  • Imaging, Three-Dimensional / methods*
  • Male
  • Pattern Recognition, Automated / methods*
  • Prostatic Neoplasms / diagnosis*
  • Radiography, Interventional / methods
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Subtraction Technique*
  • Surgery, Computer-Assisted / methods*