New MR sequences (diffusion, perfusion, spectroscopy) in brain tumours

Pediatr Radiol. 2010 Jun;40(6):999-1009. doi: 10.1007/s00247-010-1613-y. Epub 2010 Apr 30.

Abstract

While MRI has been instrumental in significantly improving care in children harbouring brain tumours, conventional sequences lack information regarding functional parameters including cellularity, haemodynamics and metabolism. Advanced MR imaging modalities, such as diffusion (including diffusion tensor imaging and fibre tractography), perfusion and spectroscopy have significantly improved our understanding of the physiopathology of brain tumours and have provided invaluable additional information for treatment planning and monitoring of treatment results. The contribution of these methods to the characterization of brain neoplasms in children is the focus of the present manuscript.

Publication types

  • Review

MeSH terms

  • Biomarkers, Tumor / analysis*
  • Brain Neoplasms / diagnosis*
  • Brain Neoplasms / metabolism*
  • Diffusion Magnetic Resonance Imaging / methods*
  • Diffusion Magnetic Resonance Imaging / trends*
  • Humans
  • Magnetic Resonance Spectroscopy / methods*

Substances

  • Biomarkers, Tumor