[Renal effects of combined anti-hypertensive treatments]

Recenti Prog Med. 2010 Feb;101(2):70-7.
[Article in Italian]

Abstract

ACE inhibitors and angiotensin receptor blockers confer renal protection in proteinuric nephropaties, but recently worsening of renal outcomes has been reported in non-proteinuric patients treated with a combination of ramipril and telmisartan, compared to ramipril only. In view of these apparently contradictory data, the review wants to shed light on treatment modalities of patients with hypertension and chronic kidney disease.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Amides / administration & dosage
  • Amides / adverse effects
  • Amides / therapeutic use
  • Angiotensin II Type 1 Receptor Blockers / administration & dosage
  • Angiotensin II Type 1 Receptor Blockers / adverse effects
  • Angiotensin II Type 1 Receptor Blockers / therapeutic use
  • Angiotensin-Converting Enzyme Inhibitors / administration & dosage
  • Angiotensin-Converting Enzyme Inhibitors / adverse effects
  • Angiotensin-Converting Enzyme Inhibitors / therapeutic use
  • Antihypertensive Agents / administration & dosage
  • Antihypertensive Agents / adverse effects
  • Antihypertensive Agents / classification
  • Antihypertensive Agents / pharmacology*
  • Antihypertensive Agents / therapeutic use
  • Diuretics / administration & dosage
  • Diuretics / adverse effects
  • Diuretics / therapeutic use
  • Fumarates / administration & dosage
  • Fumarates / adverse effects
  • Fumarates / therapeutic use
  • Glomerular Filtration Rate / drug effects
  • Humans
  • Hypertension / complications
  • Hypertension / drug therapy*
  • Kidney / drug effects*
  • Kidney / physiopathology
  • Kidney Diseases / chemically induced
  • Kidney Diseases / complications
  • Kidney Diseases / prevention & control*
  • Kidney Diseases / urine
  • Kidney Failure, Chronic / complications
  • Meta-Analysis as Topic
  • Natriuresis / drug effects
  • Proteinuria / etiology
  • Proteinuria / prevention & control
  • Randomized Controlled Trials as Topic
  • Water-Electrolyte Imbalance / chemically induced

Substances

  • Amides
  • Angiotensin II Type 1 Receptor Blockers
  • Angiotensin-Converting Enzyme Inhibitors
  • Antihypertensive Agents
  • Diuretics
  • Fumarates
  • aliskiren