Group-based psychosocial intervention for bipolar disorder: randomised controlled trial

Br J Psychiatry. 2010 May;196(5):383-8. doi: 10.1192/bjp.bp.108.058263.

Abstract

Background: Psychosocial interventions have the potential to enhance relapse prevention in bipolar disorder.

Aims: To evaluate a manualised group-based intervention for people with bipolar disorder in a naturalistic setting.

Method: Eighty-four participants were randomised to receive the group-based intervention (a 12-week programme plus three booster sessions) or treatment as usual, and followed up with monthly telephone interviews (for 9 months post-intervention) and face-to-face interviews (at baseline, 3 months and 12 months).

Results: Participants who received the group-based intervention were significantly less likely to have a relapse of any type and spent less time unwell. There was a reduced rate of relapse in the treatment group for pooled relapses of any type (hazard ratio 0.43, 95% CI 0.20-0.95; t(343) = -2.09, P = 0.04).

Conclusions: This study suggests that the group-based intervention reduces relapse risk in bipolar disorder.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Antimanic Agents / therapeutic use
  • Bipolar Disorder / prevention & control
  • Bipolar Disorder / therapy*
  • Combined Modality Therapy
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Psychotherapy, Group / methods*
  • Secondary Prevention
  • Survival Analysis
  • Treatment Outcome

Substances

  • Antimanic Agents