Allogeneic haematopoietic cell transplantation with nonmyeloablative conditioning in Denmark

Dan Med Bull. 2010 May;57(5):A4146.

Abstract

Introduction: Haematopoietic cell transplantation with nonmyeloablative conditioning (NMC-HCT) is used in the treatment of haematological malignancies.

Material and methods: Use of NMC-HCT in Denmark from 2000-07 was examined.

Results: Unrelated donor searches resulted in a suitable donor in 75% of cases of which 36% were transplanted. Among 244 patients referred for NMC-HCT, 72% were transplanted. There was a significant difference in the number of NMC-HCTs between national regions. Increasing waiting time resulted in 22% of the referred patients being taken off the waiting list without NMC-HCT.

Conclusion: Some patients may have had a chance of cure if they had been transplanted without delay.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Hematologic Neoplasms / mortality
  • Hematologic Neoplasms / therapy*
  • Hematopoietic Stem Cell Transplantation*
  • Histocompatibility
  • Humans
  • Survival Rate
  • Transplantation Conditioning* / methods
  • Transplantation, Homologous
  • Waiting Lists