Adverse events in analgesic treatment with tramadol associated with CYP2D6 extensive-metaboliser and OPRM1 high-expression variants

Ann Rheum Dis. 2010 Oct;69(10):1889-90. doi: 10.1136/ard.2009.124347. Epub 2010 May 5.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Analgesics, Opioid / adverse effects*
  • Cytochrome P-450 CYP2D6 / genetics*
  • Genetic Predisposition to Disease
  • Humans
  • Nausea / chemically induced
  • Receptors, Opioid, mu / genetics*
  • Tramadol / adverse effects*
  • Vomiting / chemically induced

Substances

  • Analgesics, Opioid
  • OPRM1 protein, human
  • Receptors, Opioid, mu
  • Tramadol
  • Cytochrome P-450 CYP2D6