Dilated cardiomyopathy in epidermolysis bullosa

Dermatol Clin. 2010 Apr;28(2):347-51, xi. doi: 10.1016/j.det.2010.02.002.

Abstract

Dilated cardiomyopathy (DC) is a rare but potentially fatal complication of epidermolysis bullosa. No clear cause for it has been identified, but iron overload, low carnitine, low selenium, concomitant viral illness, chronic anemia, and medications have been proposed as possible contributors to the development of DC in reported cases. Early detection allows for medical treatment that delays clinical progression and prolongs survival.

Publication types

  • Review

MeSH terms

  • Cardiomyopathy, Dilated / etiology*
  • Cardiomyopathy, Dilated / metabolism
  • Cardiomyopathy, Dilated / therapy*
  • Carnitine / deficiency
  • Epidermolysis Bullosa / complications*
  • Epidermolysis Bullosa / metabolism
  • Humans
  • Selenium / deficiency

Substances

  • Selenium
  • Carnitine