Abstract
We assessed the relationship between strain type, clinical factors, and outcome in 128 patients with Clostridium difficile infection. Strain type was not associated with any outcome measure. On multivariate analysis, ischemic heart disease and hypoalbuminemia predicted death. Metronidazole treatment in severe disease was associated with a higher rate of treatment failure and death.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Aged
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Aged, 80 and over
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Anti-Infective Agents / adverse effects
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Clostridioides difficile / classification*
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Clostridium Infections / microbiology
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Clostridium Infections / mortality*
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Feces / microbiology
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Female
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Hospitals, Teaching
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Humans
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Male
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Metronidazole / adverse effects
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Prospective Studies
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Risk Factors
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Treatment Outcome
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United Kingdom / epidemiology
Substances
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Anti-Infective Agents
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Metronidazole