Towards the synthesis of a Yersinia pestis cell wall polysaccharide: enantioselective synthesis of an L-glycero-D-manno-heptose building block

Chem Commun (Camb). 2010 Jun 21;46(23):4106-8. doi: 10.1039/c000784f. Epub 2010 May 7.

Abstract

A short and enantioselective de novo synthesis of an L-glycero-D-manno-heptose building block for the total synthesis of a Yersinia pestis cell wall polysaccharide is described.

MeSH terms

  • Cell Wall / chemistry*
  • Heptoses / chemical synthesis*
  • Isomerism
  • Molecular Structure
  • Polysaccharides / chemical synthesis*
  • Yersinia pestis / chemistry*

Substances

  • Heptoses
  • Polysaccharides
  • glycero-manno-heptose