[Allopurinol-induced hypersensitivity syndrome resulting in death]

Med Klin (Munich). 2010 Apr;105(4):262-6. doi: 10.1007/s00063-010-1037-3.
[Article in German]

Abstract

The present report describes the case of a 67-year-old patient who developed an allopurinol-induced hypersensitivity syndrome (AHS) with toxic epidermal necrolysis and subsequently died of septic multiorgan failure. Considering the increasing prescription rate of allopurinol, the present case report intends to demonstrate the underestimated threat of AHS.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Aged
  • Allopurinol / toxicity*
  • Diagnosis, Differential
  • Drug Hypersensitivity / diagnosis
  • Drug Hypersensitivity / etiology*
  • Drug Hypersensitivity / therapy
  • Fatal Outcome
  • Gout / drug therapy*
  • Humans
  • Kidney Failure, Chronic / complications
  • Kidney Failure, Chronic / diagnosis
  • Kidney Failure, Chronic / therapy
  • Male
  • Multiple Organ Failure / chemically induced*
  • Multiple Organ Failure / diagnosis
  • Multiple Organ Failure / therapy
  • Recurrence
  • Stevens-Johnson Syndrome / diagnosis
  • Stevens-Johnson Syndrome / etiology*
  • Stevens-Johnson Syndrome / therapy

Substances

  • Allopurinol