Abstract
Two new diketopiperazine metabolites, novoamauromine (1) and ent-cycloechinulin (2) have been isolated from Aspergillus novofumigatus CBS117520. The structures of 1 and 2 were established on the basis of spectroscopic and chemical investigation, including a detailed comparison of the spectroscopic and physico-chemical data of amauromine (3) and cycloechinulin (4).
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antifungal Agents* / chemistry
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Antifungal Agents* / pharmacology
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Antineoplastic Agents* / chemistry
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Antineoplastic Agents* / pharmacology
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Aspergillus / chemistry*
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Cell Line, Tumor
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Chromatography, Liquid
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Diketopiperazines / chemistry*
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Fungi / drug effects
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Humans
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Magnetic Resonance Spectroscopy
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Microbial Sensitivity Tests
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Molecular Structure
Substances
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Antifungal Agents
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Antineoplastic Agents
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Diketopiperazines
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ent-cycloechinulin
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novoamauromine