Abstract
Nine imipenem-resistant Pseudomonas aeruginosa isolates were found to contain a variety of metallo-beta-lactamase genes, including bla(IMP-1), bla(IMP-7), bla(VIM-2), bla(VIM-6), and the novel bla(IMP-26). Multilocus sequence typing showed a diversity of sequence types. Comparison with isolates from an earlier study showed that the epidemic clones from 2000 have not become established.
MeSH terms
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Bacterial Proteins / genetics*
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Bacterial Typing Techniques
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Carbapenems / pharmacology*
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Electrophoresis, Gel, Pulsed-Field
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Genotype
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Humans
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Molecular Sequence Data
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Pseudomonas aeruginosa* / drug effects
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Pseudomonas aeruginosa* / genetics
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Sequence Analysis, DNA / methods
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Singapore
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beta-Lactam Resistance / genetics
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beta-Lactamases / genetics*
Substances
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Bacterial Proteins
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Carbapenems
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beta-Lactamases