Impaired abstract thinking may discriminate between normal aging and vascular mild cognitive impairment

Arq Neuropsiquiatr. 2010 Apr;68(2):179-84. doi: 10.1590/s0004-282x2010000200005.

Abstract

Objective: Cerebrovascular disease (CVD) is associated with cognitive deficits. This cross-sectional study examines differences among healthy elderly controls and patients with vascular mild cognitive impairment (VaMCI) and vascular dementia (VaD) in performances on CAMCOG subscales.

Method: Elderly individuals (n=61) were divided into 3 groups, according to cognitive and neuroimaging status: 16 controls, 20 VaMCI and 25 VaD. VaMCI and VaD individuals scored over 4 points on the Hachinski Ischemic Scale.

Results: Significant differences in total CAMCOG scores were observed across the three groups (p<0.001). VaD subjects performed worse than those with VaMCI in most CAMCOG subscales (p<0.001). All subscales showed differences between controls and VaD (p<0.001). Performance on abstract thinking showed difference between VaMCI and controls (p<0.001).

Conclusion: CAMCOG discriminated controls from VaMCI and VaD. Assessment of abstract thinking may be useful as a screening item for diagnosis of VaMCI.

MeSH terms

  • Aged
  • Aging / physiology*
  • Case-Control Studies
  • Cognition Disorders / diagnosis*
  • Cognition Disorders / physiopathology
  • Cross-Sectional Studies
  • Dementia, Vascular / diagnosis*
  • Dementia, Vascular / physiopathology
  • Educational Status
  • Female
  • Humans
  • Male
  • Neuropsychological Tests
  • Psychiatric Status Rating Scales
  • Thinking / physiology*