Allosteric AKT inhibitors as a targeted cancer therapy

Cancer Biol Ther. 2010 Apr 1;9(7):504-6. doi: 10.4161/cbt.9.7.11356. Epub 2010 Apr 1.

Author

Jihye Yun¹

Affiliation

¹ Ludwig Center for Cancer Genetics and Therapeutics, and Howard Hughes Medical Institute, Johns Hopkins Kimmel Cancer Center, Baltimore, MD 21231, USA. [email protected]

PMID: 20484970
DOI: 10.4161/cbt.9.7.11356

No abstract available

Publication types

Comment

MeSH terms

Allosteric Regulation
Animals
Humans
Neoplasms / drug therapy
Neoplasms / metabolism
Neoplasms / prevention & control*
Protein Kinase Inhibitors / therapeutic use*
Proto-Oncogene Proteins c-akt / antagonists & inhibitors*
Proto-Oncogene Proteins c-akt / metabolism

Substances

Protein Kinase Inhibitors
Proto-Oncogene Proteins c-akt