Information transfer through the spontaneous baroreflex in healthy humans

Methods Inf Med. 2010;49(5):506-10. doi: 10.3414/ME09-02-0036. Epub 2010 May 21.

Abstract

Objectives: This study assesses the information transfer through the spontaneous baroreflex (i.e. through the pathway linking systolic arterial pressure to heart period) during an experimental condition soliciting baroreflex (i.e. head-up tilt).

Methods: The information transfer was calculated as the conditional entropy of heart period given systolic arterial pressure using a mutual neighbor approach and uniform quantization. The information transfer was monitored as a function of the forecasting time k.

Results: We found that during head-up tilt the information transfer at k = 0 decreased but the rate of rise of information transfer as a function of k was faster.

Conclusions: We suggest that the characterization of the information transfer from systolic arterial pressure to heart period might complement the traditional characterization of the spontaneous baroreflex based on transfer function analysis.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Baroreflex / physiology*
  • Data Interpretation, Statistical
  • Electrocardiography*
  • Entropy
  • Female
  • Humans
  • Male
  • Middle Aged
  • Photoplethysmography*
  • Reference Values
  • Signal Processing, Computer-Assisted
  • Systole / physiology
  • Tilt-Table Test
  • Young Adult