Tularemia is a rare zoonosis. There are a few ways of transmission of F. tularensis known: from the most common: contaminated meat, water, inhalation to rarely considered as insect or tick bite. insect bites are known. The disease may present non specific clinical picture, its course may be acute or chronic. Because of polymorphism of clinical picture specific treatment is often delayed. In our paper we present cases of patients, who were diagnosed with tularemia due to horse-fly or tick bite.