OPCAB in acute coronary syndrome: predictors of intra-aortic balloon pump use

Indian Heart J. 2009 May-Jun;61(3):249-53.

Abstract

Aim: Acute coronary syndrome (ACS) patients undergoing offpump coronary artery bypass (OPCAB) often require intra-aortic balloon pump (IABP) support. Indications and timing of IABP insertion are controversial. A study was done to determine criteria for predicting the use of IABP in these patients.

Method: 46 patients were operated for ACS within one week of event between January 2004 and July 2006 and categorized into, Unstable angina (UA) (n=25), with ongoing pain after late admission to emergency room (>6 hours) and acute myocardial infarction (AMI) (n=21) with AMI within 7 days of event.

Results: There was no statistical difference in the demographic data of two groups. UA group had higher incidence of mitral regurgitation preoperatively (p = 0.004) which improved postoperatively (p = 0.1). IABP was usedpreoperatively more in AMI group (10 vs. 6, p = 0.03). Multivariate analysis revealed pressure ratio of mean pulmonary and systemic arteries as a predictor of IABP use (p = 0.01, odds ratio 19.4, 95% CI 1.9-190). There is a significant positive correlation (r = 0.519) between IABP use and ratio of mean pulmonary and systemic arterial pressures (p = 0.004) with cutoff value at 0.40.

Conclusion: Ratio of mean pulmonary and systemic artery of > 0.40 indicates preoperative use of IABP to complete the operation safely.

MeSH terms

  • Acute Coronary Syndrome / diagnostic imaging
  • Acute Coronary Syndrome / surgery
  • Acute Coronary Syndrome / therapy*
  • Adult
  • Aged
  • Confidence Intervals
  • Female
  • Humans
  • Incidence
  • Intra-Aortic Balloon Pumping / statistics & numerical data*
  • Logistic Models
  • Male
  • Middle Aged
  • Mitral Valve Insufficiency
  • Multivariate Analysis
  • Odds Ratio
  • Risk Factors
  • Statistics as Topic
  • Time Factors
  • Ultrasonography