Abstract
We evaluated the ability of a commercial microarray system (Check KPC/ESBL; Check-Points Health BV) to detect clinically important class A beta-lactamase genes. A total of 106 Gram-negative strains were tested. The following sensitivity and specificity results were recorded, respectively: for bla(SHV), 98.8% and 100%; for bla(TEM), 100% and 96.4%; and for bla(CTX-M) and bla(KPC), 100% and 100%.
Publication types
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Comparative Study
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Bacterial Proteins / genetics*
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DNA, Bacterial / chemistry
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Evaluation Studies as Topic
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Gram-Negative Bacteria / genetics*
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Gram-Negative Bacterial Infections / microbiology
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Humans
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Oligonucleotide Array Sequence Analysis / methods*
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Polymerase Chain Reaction / methods
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Sensitivity and Specificity
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Sequence Analysis, DNA / methods*
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beta-Lactamases / genetics*
Substances
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Bacterial Proteins
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DNA, Bacterial
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beta-Lactamases