Thrombopoietin receptor activation, thrombopoietin mimetic drugs, and hereditary thrombocytosis: remarks on bone marrow fibrosis

J Clin Oncol. 2010 Jul 1;28(19):e317-8. doi: 10.1200/JCO.2010.29.0387. Epub 2010 Jun 1.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Benzoates / adverse effects
  • Benzoates / therapeutic use
  • Humans
  • Hydrazines / adverse effects
  • Hydrazines / therapeutic use
  • Mutation
  • Primary Myelofibrosis / chemically induced
  • Pyrazoles / adverse effects
  • Pyrazoles / therapeutic use
  • Receptors, Fc / therapeutic use
  • Receptors, Thrombopoietin / agonists
  • Receptors, Thrombopoietin / genetics*
  • Receptors, Thrombopoietin / metabolism
  • Recombinant Fusion Proteins / adverse effects
  • Recombinant Fusion Proteins / therapeutic use
  • Thrombocytopenia / blood
  • Thrombocytopenia / drug therapy
  • Thrombocytosis / genetics*
  • Thrombocytosis / metabolism
  • Thrombopoietin / adverse effects
  • Thrombopoietin / therapeutic use
  • Transcriptional Activation / drug effects

Substances

  • Benzoates
  • Hydrazines
  • Pyrazoles
  • Receptors, Fc
  • Receptors, Thrombopoietin
  • Recombinant Fusion Proteins
  • Thrombopoietin
  • romiplostim
  • eltrombopag