Clinical and radiographic improvement following cerebral fat emboli

Neurocrit Care. 2011 Aug;15(1):190-3. doi: 10.1007/s12028-010-9388-4.

Abstract

Background: Cerebral fat embolism is a well-described complication associated with long-bone fracture. However, with contemporary imaging, there is a distinct magnetic resonance imaging (MRI) pattern emerging.

Methods: The authors describe a case and briefly review the proposed etiology, clinical and radiographic diagnosis, treatment and outcome of cerebral fat embolism.

Results: A 21-year-old male sustained a femur fracture after a motor vehicle accident and had delayed pulmonary and neurological deterioration 2 days following injury. MRI of the brain demonstrated a pattern of diffuse punctuate hyperintense signal on T2-weighted and diffusion weighted imaging. This "starfield" pattern reversed on follow-up MRI at 1 month, and occurred in conjunction with remarkable clinical recovery.

Conclusion: This case highlights the MRI findings associated with fat embolism, their reversibility, and offers insight into the significant clinical improvement that may occur in such patients.

Publication types

  • Case Reports

MeSH terms

  • Embolism, Fat / diagnosis*
  • Embolism, Fat / etiology
  • Embolism, Fat / therapy*
  • Femoral Fractures / complications
  • Femoral Fractures / diagnosis
  • Femoral Fractures / therapy
  • Humans
  • Intracranial Embolism / diagnosis*
  • Intracranial Embolism / etiology
  • Intracranial Embolism / therapy*
  • Magnetic Resonance Imaging
  • Male
  • Young Adult