Abstract
Basophils have recently been identified as antigen-presenting cells that are required for optimal antibody responses. New findings now show that activation of these cells can amplify autoimmune responses in systemic lupus erythematosus (SLE).
MeSH terms
-
Animals
-
Autoantibodies / immunology
-
Autoimmunity / immunology
-
Autoimmunity / physiology
-
Basophils / immunology*
-
Histocompatibility Antigens Class II / immunology
-
Humans
-
Immunoglobulin E / immunology
-
Lupus Nephritis / etiology
-
Lupus Nephritis / immunology*
-
Mice
-
Th2 Cells / immunology
Substances
-
Autoantibodies
-
Histocompatibility Antigens Class II
-
Immunoglobulin E