An atypical porcine proliferative enteropathy of malgrowth piglets

J Vet Med Sci. 2010 Nov;72(11):1483-5. doi: 10.1292/jvms.10-0103. Epub 2010 Jun 11.

Abstract

Two 60-day-old pigs showing clinical signs of malgrowth and diarrhea were diagnosed as atypical porcine proliferative enteropathy (PPE). The intestinal mucosal lesions in the piglets were characterized by the adenomatous proliferation of the crypt epithelium together with growth of small curved bacteria within the enterocytes. The lesions could be seen in the ileum and other portions of the intestine histologically, although no significant thickening of the gut wall could be observed grossly in the present case. The macroscopic findings are extremely important for the diagnosis of PPE, however, this paper shows that the histopathological and/or immunohistochemical findings were also critical to identify the disease.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Bacteria / growth & development
  • Bacteria / isolation & purification
  • Bacterial Vaccines / therapeutic use
  • Candida / isolation & purification
  • Candidiasis / microbiology
  • Candidiasis / pathology
  • Candidiasis / veterinary
  • Cell Division
  • Epithelial Cells / cytology
  • Epithelial Cells / microbiology
  • Epithelial Cells / pathology
  • Escherichia coli Infections / microbiology
  • Escherichia coli Infections / pathology
  • Escherichia coli Infections / veterinary
  • Growth Disorders / microbiology
  • Growth Disorders / pathology
  • Growth Disorders / veterinary*
  • Ileum / cytology
  • Ileum / pathology
  • Intestinal Diseases / immunology
  • Intestinal Diseases / microbiology
  • Intestinal Diseases / pathology
  • Intestinal Diseases / veterinary*
  • Intestinal Mucosa / cytology
  • Intestinal Mucosa / pathology
  • Reference Values
  • Swine
  • Swine Diseases / immunology
  • Swine Diseases / microbiology
  • Swine Diseases / pathology*

Substances

  • Bacterial Vaccines