Intermolecular C-O addition of carboxylic acids to arynes

Org Lett. 2010 Jul 16;12(14):3117-9. doi: 10.1021/ol101017z.

Abstract

A novel, efficient, and expedient route to biologically and pharmaceutically important o-hydroxyaryl ketones, xanthones, 4-chromanones, and flavones has been developed starting from readily available carboxylic acids and commercially available o-(trimethylsilyl)aryl triflates.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Benzene / chemistry*
  • Carbon / chemistry*
  • Carboxylic Acids / chemistry*
  • Oxygen / chemistry*

Substances

  • Carboxylic Acids
  • Carbon
  • Benzene
  • Oxygen