Septic shock caused by Plesiomonas shigelloides in a patient with sickle beta-zero thalassemia

Heart Lung. 2010 Jul-Aug;39(4):335-9. doi: 10.1016/j.hrtlng.2009.06.015. Epub 2009 Sep 11.

Abstract

Invasive infection and extraintestinal complications are rarely caused by Plesiomonas shigelloides, a waterborne bacterium belonging to the Vibrionaceae family. We report a case of a 16-year-old female patient with sickle beta-zero thalassemia who survived septic shock caused by P. shigelloides associated with secondary acute respiratory distress syndrome and disseminated intravascular coagulation. Treatment with a carbapenem was successful, and the patient recovered without any sequelae. The previous reports of P. shigelloides sepsis are cited, and possible pathogenic mechanisms are discussed.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Anti-Bacterial Agents / therapeutic use
  • Anti-Infective Agents / therapeutic use
  • Carbapenems / therapeutic use*
  • Ceftriaxone / therapeutic use
  • Clarithromycin / therapeutic use
  • Critical Illness
  • Disseminated Intravascular Coagulation
  • Female
  • Gram-Negative Bacterial Infections / drug therapy*
  • Gram-Negative Bacterial Infections / etiology
  • Gram-Negative Bacterial Infections / microbiology
  • Hemoglobin, Sickle / analysis*
  • Humans
  • Imipenem / therapeutic use
  • Intensive Care Units
  • Metronidazole / therapeutic use
  • Plesiomonas / isolation & purification*
  • Respiratory Distress Syndrome
  • Shock, Septic / drug therapy*
  • Shock, Septic / microbiology
  • Thalassemia / complications
  • Thalassemia / drug therapy*
  • Thalassemia / microbiology

Substances

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Carbapenems
  • Hemoglobin, Sickle
  • Metronidazole
  • Imipenem
  • Ceftriaxone
  • Clarithromycin