Abstract
The versatility of copper-catalyzed alkyne-azide coupling (CuAAC) in functionalizing drug-loaded polymer nanoparticles is demonstrated via the modification of surfaces of acetylene-functionalized PNPs with folate, biotin, and gold nanoparticles.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Alkenes / chemistry
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Azides / chemistry
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Catalysis
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Copper / chemistry
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Gold / chemistry*
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Metal Nanoparticles / chemistry*
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Metal Nanoparticles / ultrastructure
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Microscopy, Electron, Transmission
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Molecular Structure
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Polymers / chemistry*
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Surface Properties
Substances
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Alkenes
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Azides
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Polymers
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Gold
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Copper