Metastatic epidural spinal cord compression

Semin Neurol. 2010 Jul;30(3):245-53. doi: 10.1055/s-0030-1255221. Epub 2010 Jun 24.

Abstract

Metastatic epidural spinal cord compression is a debilitating consequence of multiple cancer types. Early diagnosis and treatment are imperative for improving functional outcome. The authors review the epidemiology, pathophysiology, clinical features, and diagnostic evaluation of metastatic epidural spinal cord compression. Special attention will be given to the supportive and definitive treatments available for management, and new therapeutic interventions, such as radiosurgery, will be briefly discussed as well.

Publication types

  • Review

MeSH terms

  • Animals
  • Humans
  • Practice Guidelines as Topic
  • Spinal Cord Compression / etiology*
  • Spinal Cord Compression / pathology
  • Spinal Cord Compression / therapy
  • Spinal Cord Neoplasms / secondary*
  • Spinal Cord Neoplasms / therapy