Real time optical method for localization of inclusions embedded in turbid media

Opt Express. 2010 Apr 12;18(8):7753-62. doi: 10.1364/OE.18.007753.

Abstract

A simple and fast time-domain method for localizing inclusions, fluorescent optical probes or absorbers, is presented. The method offers new possibilities for situations where complete tomographic measurements are not permitted by the examined object, for example in endoscopic examination of the human prostate or the oesophagus. Feasibility has been envisioned with a phantom study conducted on a point-like fluorochrome embedded in a diffusing medium mimicking the optical properties of biological tissues.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Fluorescent Dyes / chemistry
  • Nephelometry and Turbidimetry / instrumentation*
  • Nephelometry and Turbidimetry / methods*
  • Optical Phenomena*
  • Surface Properties
  • Time Factors

Substances

  • Fluorescent Dyes