[Propylthiouracil-induced multispecific antineutrophil cytoplasmic antibodies]

A Servonnet; C Garcia-Hejl; F Banal; J Ramirez; E Fontan

doi:10.1016/j.revmed.2009.08.020

[Propylthiouracil-induced multispecific antineutrophil cytoplasmic antibodies]

Rev Med Interne. 2010 Oct;31(10):e9-e10. doi: 10.1016/j.revmed.2009.08.020. Epub 2010 Jun 1.

[Article in French]

Authors

A Servonnet¹, C Garcia-Hejl, F Banal, J Ramirez, E Fontan

Affiliation

¹ Service de biochimie, hôpital d'instruction des armées du Val-de-Grâce, 75005 Paris, France. [email protected]

PMID: 20605662
DOI: 10.1016/j.revmed.2009.08.020

Abstract

We report the case of a 28-year-old woman who presented with arthralgia during a treatment with propylthiouracil (PTU) for hyperthyroidism. Detection of antineutrophil cytoplasmic antibodies (ANCA) against myeloperoxidase, proteinase 3 and elastase led to suspect PTU induced vasculitis.

Publication types

Case Reports
English Abstract

MeSH terms

Adult
Antibodies, Antineutrophil Cytoplasmic / immunology*
Antithyroid Agents / adverse effects*
Female
Humans
Propylthiouracil / adverse effects*
Vasculitis / chemically induced*
Vasculitis / immunology*

Substances

Antibodies, Antineutrophil Cytoplasmic
Antithyroid Agents
Propylthiouracil