Abstract
Primary cutaneous squamous cell carcinoma (SCC) is a malignant tumor that arises from keratinizing cells of the epidermis or its appendages. We present a patient with cutaneous SCC on the left instep with metastases to multiple lymph nodes in the para-aortic, iliac and groin region. We chose a combination of surgery and concurrent chemoradiotherapy. The chemotherapeutic agent S-1/cisplatin was selected based on results of the histoculture drug response assay. The patient responded dramatically to this multidisciplinary treatment and complete remission was achieved.
MeSH terms
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Antineoplastic Agents / therapeutic use
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Antineoplastic Combined Chemotherapy Protocols
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Carcinoma, Squamous Cell / drug therapy
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Carcinoma, Squamous Cell / pathology
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Carcinoma, Squamous Cell / radiotherapy
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Carcinoma, Squamous Cell / surgery
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Carcinoma, Squamous Cell / therapy*
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Cisplatin / therapeutic use
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Combined Modality Therapy / methods
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Drug Combinations
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Humans
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Lymphatic Metastasis
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Male
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Middle Aged
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Oxonic Acid / therapeutic use
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Skin Neoplasms / drug therapy
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Skin Neoplasms / pathology
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Skin Neoplasms / radiotherapy
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Skin Neoplasms / surgery
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Skin Neoplasms / therapy*
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Tegafur / therapeutic use
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Treatment Outcome
Substances
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Antineoplastic Agents
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Drug Combinations
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S 1 (combination)
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Tegafur
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Oxonic Acid
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Cisplatin