Supporting retrieval of diverse biomedical data using evidence-aware queries

J Biomed Inform. 2010 Dec;43(6):873-82. doi: 10.1016/j.jbi.2010.07.005. Epub 2010 Jul 17.

Abstract

Though there have been many advances in providing access to linked and integrated biomedical data across repositories, developing methods which allow users to specify ambiguous and exploratory queries over disparate sources remains a challenge to extracting well-curated or diversely-supported biological information. In the following work, we discuss the concepts of data coverage and evidence in the context of integrated sources. We address diverse information retrieval via a simple framework for representing coverage and evidence that operates in parallel with an arbitrary schema, and a language upon which queries on the schema and framework may be executed. We show that this approach is capable of answering questions that require ranged levels of evidence or triangulation, and demonstrate that appropriately-formed queries can significantly improve the level of precision when retrieving well-supported biomedical data.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Biomedical Research
  • Databases, Factual*
  • Information Storage and Retrieval / methods*
  • Internet
  • Semantics