Diagnosis and counselling of patients with acute HIV infection in South Africa

Sex Transm Infect. 2011 Feb;87(1):71-2. doi: 10.1136/sti.2009.041475. Epub 2010 Jul 18.

Abstract

Objectives: To identify, diagnose and counsel patients with acute HIV infection (AHI) during routine HIV testing in South Africa.

Methods: Patients with sexually transmitted infection and clients undergoing voluntary counselling and testing who were negative on rapid HIV antibody tests at a public youth clinic were recruited to the study and tested using HIV-1 PCR and third-generation ELISA. Results were made available at 1 week. Text message reminders and phone calls were employed to encourage patients to return for results. Patients with AHI were additionally visited at home.

Results: 902 participants were enrolled over the course of 1 year, reporting high levels of sexual risk behaviour, including 66.7% who did not use a condom at last sex. Six (0.67%) were diagnosed with AHI. Results and counselling were delivered to 62.3% of participants and all six patients with AHI.

Conclusions: It is possible to perform routine diagnosis and counselling for acute HIV infection in a limited-resource setting. Provider outreach to patients may help in delivering results to a high proportion of patients, but will probably add to the already substantial cost of testing.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Adult
  • Condoms / statistics & numerical data
  • Counseling*
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • HIV Infections / diagnosis*
  • HIV-1*
  • Humans
  • Male
  • Polymerase Chain Reaction
  • Sexual Partners
  • South Africa
  • Unsafe Sex / statistics & numerical data
  • Young Adult