Frequency-difference MIT imaging of cerebral haemorrhage with a hemispherical coil array: numerical modelling

Physiol Meas. 2010 Aug;31(8):S111-25. doi: 10.1088/0967-3334/31/8/S09. Epub 2010 Jul 21.

Abstract

The feasibility of detecting a cerebral haemorrhage with a hemispherical MIT coil array consisting of 56 exciter/sensor coils of 10 mm radius and operating at 1 and 10 MHz was investigated. A finite difference method combined with an anatomically realistic head model comprising 12 tissue types was used to simulate the strokes. Frequency-difference images were reconstructed from the modelled data with different levels of the added phase noise and two types of a priori boundary errors: a displacement of the head and a size scaling error. The results revealed that a noise level of 3 m degrees (standard deviation) was adequate for obtaining good visualization of a peripheral stroke (volume approximately 49 ml). The simulations further showed that the displacement error had to be within 3-4 mm and the scaling error within 3-4% so as not to cause unacceptably large artefacts on the images.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cerebral Hemorrhage / complications
  • Cerebral Hemorrhage / diagnosis*
  • Humans
  • Image Processing, Computer-Assisted
  • Magnetics*
  • Models, Anatomic*
  • Stroke / complications
  • Stroke / diagnosis
  • Tomography / instrumentation*
  • Tomography / methods