Abstract
Bullous systemic lupus erythematosus is a subepidermal blistering disease that occurs only rarely in a subset of patients with systemic lupus erythematosus and even less commonly in pediatric patients. Autoimmunity in bullous systemic lupus erythematosus is characterized by the presence of circulating anti-type VII collagen antibodies. We report here a case of a child whose initial systemic lupus erythematosus presentation was a diffuse bullous eruption.
MeSH terms
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Adolescent
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Anti-Inflammatory Agents / therapeutic use
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Antibodies, Antinuclear / blood
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Autoantibodies / blood
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Collagen Type VII / immunology
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Dapsone / therapeutic use
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Female
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Humans
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Hydroxychloroquine / therapeutic use
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Lupus Erythematosus, Cutaneous / diagnosis*
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Lupus Erythematosus, Cutaneous / drug therapy
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Lupus Erythematosus, Cutaneous / immunology
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Lupus Erythematosus, Cutaneous / pathology
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Lupus Erythematosus, Systemic / diagnosis*
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Lupus Erythematosus, Systemic / drug therapy
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Lupus Erythematosus, Systemic / immunology
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Lupus Erythematosus, Systemic / pathology
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Methylprednisolone / therapeutic use
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Mycophenolic Acid / analogs & derivatives
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Mycophenolic Acid / therapeutic use
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Prednisone / therapeutic use
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Skin Diseases, Vesiculobullous / diagnosis*
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Skin Diseases, Vesiculobullous / drug therapy
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Skin Diseases, Vesiculobullous / immunology
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Skin Diseases, Vesiculobullous / pathology
Substances
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Anti-Inflammatory Agents
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Antibodies, Antinuclear
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Autoantibodies
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Collagen Type VII
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Hydroxychloroquine
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Dapsone
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Mycophenolic Acid
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Prednisone
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Methylprednisolone