Bismuth subgallate as a topical hemostatic agent at palatal donor sites

Quintessence Int. 2010 Sep;41(8):645-649.

Abstract

Objective: To present bismuth subgallate as a simplified and efficient method for promoting hemostasis at palatal donor sites, as evaluated by measuring hemostasis time and delayed bleeding.

Method and materials: Ten patients received the bismuth subgallate paste as a topical hemostatic agent, while another 10 patients received moistened gauze pressure. The time to obtain complete hemostasis, defined as no visual bleeding, was recorded for each subject.

Results: Bismuth subgallate paste was found to decrease hemostasis time, when compared with moistened gauze pressure. The mean hemostasis time for the bismuth subgallate group was significantly shorter (2.6 +/- 0.7 minutes) when compared to the moistened gauze group (7.2 +/- 1.4 minutes). While delayed bleeding was observed in the moistened gauze group, no statistically significant difference was found between the groups (P = .10).

Conclusion: The use of bismuth subgallate as a topical hemostatic for palatal wounds may be an option when performing free soft tissue grafts.

Publication types

  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Administration, Topical
  • Adult
  • Bleeding Time
  • Female
  • Gallic Acid / administration & dosage
  • Gallic Acid / analogs & derivatives*
  • Gallic Acid / therapeutic use
  • Hemostatics / administration & dosage
  • Hemostatics / therapeutic use*
  • Humans
  • Male
  • Middle Aged
  • Mouth Mucosa / transplantation*
  • Ointments
  • Organometallic Compounds / administration & dosage
  • Organometallic Compounds / therapeutic use*
  • Palate, Hard / surgery*
  • Postoperative Hemorrhage / prevention & control
  • Pressure
  • Tissue and Organ Harvesting*
  • Young Adult

Substances

  • Hemostatics
  • Ointments
  • Organometallic Compounds
  • Gallic Acid
  • bismuth subgallate