[Catecholaminergic polymorphic ventricular tachycardia is a rare inherited heart disease]

Ugeskr Laeger. 2010 Aug 2;172(31):2140-4.
[Article in Danish]

Abstract

Catecholaminergic polymorphic ventricular tachycardia is a rare inherited heart disease, which can lead to life-threatening ventricular arrhythmias in patients with a structurally normal heart. The age of onset is usually between two and 12 years and the initial symptom is frequently syncope or cardiac arrest. The arrhythmias are usually triggered by exercise or emotional affection. The diagnosis is often made using exercise electrocardiogram, which typically triggers arrhythmias. The treatment consists of beta blockers, frequently in combination with implantation of a cardioverter-defibrillator.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Catecholamines / physiology
  • Child
  • Child, Preschool
  • Diagnosis, Differential
  • Heart Arrest / diagnosis
  • Humans
  • Mutation
  • Ryanodine Receptor Calcium Release Channel / genetics
  • Syncope / diagnosis
  • Tachycardia, Ventricular / congenital*
  • Tachycardia, Ventricular / diagnosis
  • Tachycardia, Ventricular / therapy

Substances

  • Catecholamines
  • Ryanodine Receptor Calcium Release Channel