Endovascular brachytherapy with (192)Ir and (188)Re to treat de novo and recurrent infrainguinal restenoses

J Cardiovasc Surg (Torino). 2010 Aug;51(4):573-8.

Abstract

We present a review of the literature on endovascular brachytherapy (EVBT) after percutaneous transluminal angioplasty (PTA) in the femoropopliteal and tibial arteries. The pathophysiological changes induced by PTA and EVBT within the vessel wall, technical considerations regarding 192Ir and 188Re, the results of clinical trials, and the medication required before, during, and after EVBT are summarized.

Publication types

  • Review

MeSH terms

  • Angioplasty, Balloon / adverse effects*
  • Arterial Occlusive Diseases / radiotherapy
  • Arterial Occlusive Diseases / therapy*
  • Brachytherapy / methods*
  • Constriction, Pathologic
  • Humans
  • Iridium Radioisotopes / therapeutic use*
  • Lower Extremity / blood supply*
  • Radioisotopes / therapeutic use*
  • Recurrence
  • Rhenium / therapeutic use*
  • Treatment Outcome

Substances

  • Iridium Radioisotopes
  • Radioisotopes
  • Rhenium