Neurobrucellosis associated with syndrome of inappropriate antidiuretic hormone with resultant diabetes insipidus and hypothyroidism

J Clin Microbiol. 2010 Oct;48(10):3806-9. doi: 10.1128/JCM.00721-10. Epub 2010 Aug 11.

Abstract

Neurological involvement of the central nervous system in brucellosis is uncommon. We describe a rare case of meningoencephalitis due to Brucella melitensis infection, associated with the syndrome of inappropriate antidiuretic hormone secretion and leading to diabetes insipidus and hypothyroidism. Neurobrucellosis, although rare, should be considered in cases of neurological disease of unknown etiology.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Brucella melitensis / isolation & purification*
  • Brucellosis / complications*
  • Brucellosis / diagnosis*
  • Brucellosis / microbiology
  • Diabetes Insipidus / diagnosis*
  • Diabetes Insipidus / etiology
  • Humans
  • Hypothyroidism / diagnosis*
  • Hypothyroidism / etiology
  • Male
  • Meningoencephalitis / complications*
  • Meningoencephalitis / diagnosis*
  • Meningoencephalitis / microbiology
  • Vasopressins / metabolism

Substances

  • Vasopressins