Abstract
We determined the seroprevalence of protective antibodies against Hib in Mexican children under the age of five using a standardized enzyme-linked immunosorbent assay. Hib antibodies (≥ 0.15 μg/ml) were present in 95.34% (±1.14% [seroprevalence ± standard error]) of samples. Fewer children aged 30 to 47 months had protective Hib antibody levels (91.45% ± 2.60%) than children from 12 to 29 and 48 to 59 months (97.3% ± 1.34% and 97.44% ± 1.80%, respectively).
MeSH terms
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Age Factors
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Antibodies, Bacterial / blood*
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Bacterial Capsules / immunology*
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Child, Preschool
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Enzyme-Linked Immunosorbent Assay / methods
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Enzyme-Linked Immunosorbent Assay / standards
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Haemophilus Vaccines / immunology*
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Haemophilus influenzae type b / immunology*
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Humans
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Immunization, Secondary / methods
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Infant
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Mexico
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Vaccination / methods*
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Vaccines, Conjugate / immunology
Substances
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Antibodies, Bacterial
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Haemophilus Vaccines
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Haemophilus influenzae type b polysaccharide vaccine
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Vaccines, Conjugate