Clinical relevance of sperm DNA assessment: an update

Christopher L R Barratt; Christopher J De Jonge

doi:10.1016/j.fertnstert.2010.07.1050

Clinical relevance of sperm DNA assessment: an update

Fertil Steril. 2010 Nov;94(6):1958-9. doi: 10.1016/j.fertnstert.2010.07.1050. Epub 2010 Aug 19.

Authors

Christopher L R Barratt, Christopher J De Jonge

PMID: 20723890
DOI: 10.1016/j.fertnstert.2010.07.1050

Abstract

For sperm DNA assessments to be widespread effective clinical tools, key objectives need to be urgently achieved. These include robust standardized methods, systems for training staff and ongoing quality control; and rigorous examination of the clinical outcomes. We discuss the significance of these objectives and conclude that, if achieved, the clinical utility of DNA damage assessment will be fully realized.

Publication types

Editorial
Evaluation Study

MeSH terms

DNA / analysis*
DNA / metabolism
Humans
Infertility, Male / diagnosis
Male
Meta-Analysis as Topic
Predictive Value of Tests
Review Literature as Topic
Semen Analysis / methods*
Semen Analysis / standards
Semen Analysis / statistics & numerical data
Spermatozoa / cytology
Spermatozoa / metabolism*

Substances

DNA