TAPC-promoted oxidation of sulfides and deoxygenation of sulfoxides

J Org Chem. 2010 Sep 17;75(18):6208-13. doi: 10.1021/jo1011784.

Abstract

1,3,5-Triazo-2,4,6-triphosphorine-2,2,4,4,6,6-tetrachloride (TAPC) was found to be an efficient promoter for the oxidation of sulfides and deoxygenation of sulfoxides. Excellent yields, short reaction time, easy and quick isolation of the products, solvent-free process, and excellent chemoselectivity are the main advantages of this procedure.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Azo Compounds / chemistry*
  • Molecular Structure
  • Oxidation-Reduction
  • Stereoisomerism
  • Sulfides / chemistry*
  • Sulfoxides / chemistry*

Substances

  • 1,3,5-triazo-2,4,6-triphosphorine-2,2,4,4,6,6-tetrachloride
  • Azo Compounds
  • Sulfides
  • Sulfoxides