Abstract
We studied the distribution of intermediate filament proteins during several stages of chick embryo heart development by indirect immunofluorescence and fluorescence-activated cell surface analysis. Vimentin is the predominant intermediate filament during the early stages of cardiac genesis, while desmin appears essentially with maturation. Desmin is the main subunit protein of intermediate filaments in the mature myocyte.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Chick Embryo
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Cytoskeleton / metabolism
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Desmin / genetics
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Desmin / metabolism
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Flow Cytometry
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Fluorescent Antibody Technique
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Gene Expression
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Heart / embryology*
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Intermediate Filament Proteins / genetics
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Intermediate Filament Proteins / metabolism*
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Myocardium / cytology
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Myocardium / metabolism*
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Myocardium / ultrastructure
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Vimentin / genetics
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Vimentin / metabolism
Substances
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Desmin
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Intermediate Filament Proteins
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Vimentin