Constitutional translocation t(1;17)(p36;q12-21) in a patient with neuroblastoma

Genes Chromosomes Cancer. 1990 Sep;2(3):252-4. doi: 10.1002/gcc.2870020315.

Abstract

A constitutional chromosome translocation t(1;17)(p36;q12-21) is reported in a boy with neuroblastoma. This is the first description of a cytogenetic abnormality possibly predisposing to the development of neuroblastoma.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abdominal Neoplasms / diagnosis
  • Abdominal Neoplasms / genetics*
  • Abdominal Neoplasms / pathology
  • Abdominal Neoplasms / therapy
  • Child, Preschool
  • Chromosome Banding
  • Chromosomes, Human, Pair 1*
  • Chromosomes, Human, Pair 17*
  • Ganglioneuroma / diagnosis
  • Ganglioneuroma / genetics*
  • Ganglioneuroma / pathology
  • Ganglioneuroma / therapy
  • Humans
  • Male
  • Metaphase
  • Neuroblastoma / diagnosis
  • Neuroblastoma / genetics*
  • Neuroblastoma / pathology
  • Neuroblastoma / therapy
  • Translocation, Genetic*
  • Tumor Cells, Cultured / cytology