Interaction of epothilone B (patupilone) with microtubules as detected by two-dimensional solid-state NMR spectroscopy

Angew Chem Int Ed Engl. 2010 Oct 4;49(41):7504-7. doi: 10.1002/anie.201001946.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents / isolation & purification
  • Antineoplastic Agents / pharmacology*
  • Epothilones / isolation & purification
  • Epothilones / pharmacology*
  • Humans
  • Microtubules / metabolism*
  • Microtubules / ultrastructure
  • Models, Molecular
  • Myxococcales / chemistry
  • Neoplasms / drug therapy
  • Nuclear Magnetic Resonance, Biomolecular / methods*
  • Tubulin / metabolism
  • Tubulin Modulators / isolation & purification
  • Tubulin Modulators / pharmacology*

Substances

  • Antineoplastic Agents
  • Epothilones
  • Tubulin
  • Tubulin Modulators
  • epothilone B