[Localized thoracic neuroblastoma: the role of surgery and therapeutic results. Apropos of 40 cases]

Chir Pediatr. 1990;31(3):146-51.
[Article in French]

Abstract

From 1982 to 1987, forty children with non-metastatic thoracic neuroblastoma were treated with a same therapeutic regimen. According to TNM staging, there were II CS I, 19 CS II and 10 CS III. All patients underwent surgery; thirty had primary surgical excision; in ten whose tumor were deemed uresectable, surgery was delayed until after a trial of chemotherapy. Operation was completed by several courses of chemotherapy in case of microscomic residual disease or lymph node involvement; radiotherapy was delivered in case of gross residual disease. Using this therapeutic approach. Event Free Survival is 92% with a median follow up of 40 months. Severe complications were rare and sequellae appear to be related to the disease i.e. neurologic consequence of cord compression.

Publication types

  • English Abstract

MeSH terms

  • Abdominal Neoplasms / pathology
  • Abdominal Neoplasms / surgery
  • Age Factors
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Child, Preschool
  • Combined Modality Therapy
  • Female
  • Humans
  • Infant
  • Lymphatic Metastasis
  • Male
  • Neoplasm Staging
  • Neuroblastoma / pathology
  • Neuroblastoma / radiotherapy
  • Neuroblastoma / secondary
  • Neuroblastoma / surgery*
  • Prognosis
  • Retrospective Studies
  • Survival Rate
  • Thoracic Neoplasms / pathology
  • Thoracic Neoplasms / radiotherapy
  • Thoracic Neoplasms / surgery*